I did design it to work for vanilla first, but as Shuulo observed it also works with some of my most often used mods just because I got lucky, so I thought I'd mention them as already tested. And while I was at it, I figured I might as well mention the ones I wish to make compatible.
I took the backdrops from vanilla and assigned them randomly with one of the sector soundtracks from vanilla, also randomly assigned. Except for Sol, which I made sure had Earth as a background. The fog and asteroid belts are taken from DeadAir Gate Overhaul, but I switched the fog regions for volumetric fog because the volumetric fog performs better, and I changed the color to a standard hazy fog rather than the resource-specific colors that DeadAir was going for. The reason I used his region definitions is that they have boundaries to prevent them from stretching infinitely into the distance, so the game loads up faster (I was having load times of 15 minutes using vanilla region definitions).
One thing I have noticed is that some sectors will have similarities due to the resource region placements. So, the same asteroid belt might show up multiple times. But, you probably wouldn't have noticed if I hadn't mentioned it here.